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Reducing the burden of squamous cell carcinoma in Fanconi anemia - 2013

2013 | Service Grant | Ralf Dietrich, Eunike Velleuer

Today 80% of FA patients survive beyond age 20, carrying a high risk for SCC of the oropharyngeal and anogenital regions connected with high morbidity and mortality. In addition to intrinsic genetic instability, HSCT and a number of other factors contribute to the pathogenesis of SCC. It is unclear…