Supported Research

Oral Mucosal Gene Therapy as a Prevention for FA-Associated Cancer

2022 | University of Washington, Oregon Health and Sciences University |

Amount Funded: $250,000

Individuals with FA are at an exceptionally high risk of developing squamous cell carcinomas (SCC) in non-keratinizing squamous epithelia lining the oral cavity, proximal esophagus, and anogenital region. The origins of these FA-associated cancers are not well understood. The goal of this project is to determine the potential of oral mucosal gene therapy to modify the risk for oral mucosal cancer in individuals with FA.

Researchers: Markus Grompe, Raymond Monnat, Jr., Kim Woodrow